This course provides a foundation for the use of a lifestyle approach for preventing, managing, and reversing chronic disease. Concepts explored include a Biblical perspective of health and healing, the role of lifestyle as a determinant of disease, the biological basis and scientific evidence for the use of lifestyle therapeutics, the impact of self-care and modeling of healthy lifestyles on patient health, and effective strategies for employing a lifestyle approach in advanced nursing practice. Eight essentials of optimal health as integral components of a healthy lifestyle are examined through the use of the CREATION Life model.